MendelSearch is a component of the umbrella OpenMendel project. This package performs function optimization, and permits bounds and linear constraints to be imposed on parameters and, in statistical applications, computes asymptotic standard errors and correlations of parameter estimates. MendelSearch is necessary to run any OpenMendel analysis package, and you should install MendelSearch first, before you install the analysis packages. View the MendelSearch Documentation for in depth information about this package.

Installation

Note: The three OpenMendel packages (1) SnpArrays, (2) MendelSearch, and (3) MendelBase must be installed before any other OpenMendel package will run. It is easiest if these three packages are installed in the above order and before any other OpenMendel package.

Within Julia, use the package manager to install MendelSearch:

pkg> add https://github.com/OpenMendel/MendelSearch.jl.git

This package supports Julia v1.0+

Citation

If you use OpenMendel analysis packages in your research, please cite the following reference in the resulting publications:

OPENMENDEL: a cooperative programming project for statistical genetics. Zhou H, Sinsheimer JS, Bates DM, Chu BB, German CA, Ji SS, Keys KL, Kim J, Ko S, Mosher GD, Papp JC, Sobel EM, Zhai J, Zhou JJ, Lange K. Hum Genet. 2019 Mar 26. doi: 10.1007/s00439-019-02001-z. [Epub ahead of print] PMID: 30915546

Acknowledgments

This project is supported by the National Institutes of Health under NIGMS awards R01GM053275 and R25GM103774 and NHGRI award R01HG006139.